NeoNova® Transcatheter Mitral Valve Clip System

NeoNova® is a new generation transcatheter edge-to-edge repair (TEER) system in China, delivering a novel minimally invasive interventional therapy for patients suffering from mitral regurgitation. Designed for elderly patients with severe mitral regurgitation who carry high surgical risks, the product repairs diseased valves via a minimally invasive approach. It greatly reduces trauma caused by open surgery, improves patients' cardiac function and improves their quality of life.

As China's first "straight-shaped" mitral valve clip, NeoNova® features four core innovative advantages. Its original straight-shaped clamping structure effectively avoids intra-procedural risk of chordal entanglement. Equipped with an elastic self-locking mechanism, it delivers flexible and controllable clamping force, adapts to leaflet motion, and prevents leaflet laceration. The innovative small-radius steering design lowers trans-septal puncture height to accommodate complex cardiac anatomies. The up to 10 mm clip enables repair of extensive leaflet prolapse lesions frequently with just one single clip, minimizing the need for multiple clip implantation and shortening procedure duration.

The product has been validated in prospective multi-center clinical trials, with its safety and efficacy confirmed by two-year follow-up data. It is now available in numerous top-tier cardiac centers nationwide, while overseas clinical development has been initiated. Patient-centered, NeoNova® leverages robust domestic innovation to bring safe and effective minimally invasive mitral valve treatment alternatives to MR patients worldwide.